Phosgene → 2,6-Diethyl-4-nitrophenylisocyanate
反応式
[C:1](Cl)(Cl)=[O:2].[CH2:5]([C:7]1[CH:13]=[C:12]([N+:14]([O-:16])=[O:15])[CH:11]=[C:10]([CH2:17][CH3:18])[C:8]=1[NH2:9])[CH3:6]>C1(C)C=CC=CC=1>[CH2:17]([C:10]1[CH:11]=[C:12]([N+:14]([O-:16])=[O:15])[CH:13]=[C:7]([CH2:5][CH3:6])[C:8]=1[N:9]=[C:1]=[O:2])[CH3:18]参加物
4
実験手順
Excess phosgene is bubbled into a warm solution of 21.5 g (0.11 moles) of 2,6-diethyl-4-nitroaniline in toluene (250 ml). After the addition, the mixture is heated to reflux and approximately 200 ml of toluene are distilled. The remainder of the toluene is removed under vacuum and the remaining brown semi-solid is distilled under vacuum to give 2,6-diethyl-4-nitrophenylisocyanate, b.p. 135°-144° C./1 mm, as a yellow liquid which crystallized on standing.
後処理
- additionAfter the addition
- temperaturethe mixture is heated
- temperatureto reflux
- distillationapproximately 200 ml of toluene are distilled
- customThe remainder of the toluene is removed under vacuum
- distillationthe remaining brown semi-solid is distilled under vacuum
出典と根拠
- ORDレコード
- ord-f7fe7bcfb4234004b8032086d9231bf4
- 出典データセット
- uspto-grants-1979_04
- 特許番号
- US04147804
反応ノート
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