Silane, chloro(chloromethyl)dimethyl- → Chloromethyl-(2,4-difluorobenzyl)dimethylsilane

反応式

[F:1][C:2]1[CH:10]=[C:9]([F:11])[CH:8]=[CH:7][C:3]=1[CH2:4][Mg]Cl.Cl[Si:13]([CH2:16][Cl:17])([CH3:15])[CH3:14]>>[Cl:17][CH2:16][Si:13]([CH2:4][C:3]1[CH:7]=[CH:8][C:9]([F:11])=[CH:10][C:2]=1[F:1])([CH3:15])[CH3:14]

参加物

反応物 2

HCID 74393Silane, chloro(chloromethyl)dimethyl-

HCID 178505761HCID 178505761、化合物

生成物 1

HCID 22399702Chloromethyl-(2,4-difluorobenzyl)dimethylsilane収率 95%

実験手順

The title compound is prepared in 95% yield from 2,4-difluorobenzylmagnesium chloride and chlorochloromethyldimethylsilane by the method described in Example 5, Step A.

出典と根拠

ORDレコード: ord-f59ceee6259247469d1327667b400278
出典データセット: uspto-grants-1996_06
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05529988

反応ノート

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