Diethyl 2-benzylpropanedioate → 3-[2-n-Butyl-1-{(4-carboxyphenyl)methyl}-1H-imidazol-5-yl]-2-benzylpropanoic Acid
反応式
[CH2:1]([C:5]1[N:6]([CH2:12][C:13]2[CH:18]=[CH:17][C:16]([C:19]([O:21]C)=[O:20])=[CH:15][CH:14]=2)[C:7]([CH:10]=O)=[CH:8][N:9]=1)[CH2:2][CH2:3][CH3:4].[CH2:23]([CH:30](C(OCC)=O)[C:31]([O:33]CC)=[O:32])[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[CH2:1]([C:5]1[N:6]([CH2:12][C:13]2[CH:14]=[CH:15][C:16]([C:19]([OH:21])=[O:20])=[CH:17][CH:18]=2)[C:7]([CH2:10][CH:30]([CH2:23][C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[C:31]([OH:33])=[O:32])=[CH:8][N:9]=1)[CH2:2][CH2:3][CH3:4]参加物
3
実験手順
The title compound was prepared following the procedure of Example 21 using 2-n-butyl-1-[(4-carbomethoxyphenyl)methyl]-1H-imidazol-5-carboxaldehyde and diethyl benzylmalonate; mp 120°-124° C.
出典と根拠
- ORDレコード
- ord-6acf0f8f116041b38b5eca6ad0a8d3e4
- 出典データセット
- uspto-grants-1996_06