2-Nitro-4-(trifluoromethyl)phenol → 2-Amino-4-(trifluoromethyl)phenol
反応式
[N+:1]([C:4]1[CH:9]=[C:8]([C:10]([F:13])([F:12])[F:11])[CH:7]=[CH:6][C:5]=1[OH:14])([O-])=O>C(O)C.[Pt]=O>[NH2:1][C:4]1[CH:9]=[C:8]([C:10]([F:11])([F:12])[F:13])[CH:7]=[CH:6][C:5]=1[OH:14]参加物
4
実験手順
82.2 g of 6A was dissolved in 300 ml of ethanol. 0.5 g of platinum oxide catalyst was added and the mixture was hydrogenated at 50 psig. Fresh portions of catalyst were added periodically. The reaction mixture was filtered, and the filtrate was concentrated. The residue was crystallized from water to give 2-amino-4-(trifluoromethyl)phenol (6B).
後処理
- additionFresh portions of catalyst were added periodically
- filtrationThe reaction mixture was filtered
- concentrationthe filtrate was concentrated
- customThe residue was crystallized from water
出典と根拠
- ORDレコード
- ord-059b6ae66e85466a99b629334c527693
- 出典データセット
- uspto-grants-1979_08
- 特許番号
- US04164576
反応ノート
読み込み中…