Beta-Nitrostyrene → alpha-(Nitromethyl)benzyl dimethyldithiocarbamate

HRID 26136

反応式

HRID 26136 の反応式
[CH3:1][N:2]([CH3:6])[C:3](=[S:5])[S-:4].C[NH2+]C.[N+:10]([CH:13]=[CH:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)([O-:12])=[O:11]>CO>[CH3:1][N:2]([CH3:6])[C:3](=[S:4])[S:5][CH:14]([CH2:13][N+:10]([O-:12])=[O:11])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

参加物

4

反応物 2

HCID 7626Beta-NitrostyreneHCID 11728Dimethyldithiocarbamic acid, dimethylamine

生成物 1

HCID 21324598alpha-(Nitromethyl)benzyl dimethyldithiocarbamate収率 51%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

Dimethylammonium dimethyldithiocarbamate (16.6 grams, 0.10 mole) carbon disulfide (7.6 grams, 0.10 mole), and β-nitrostyrene (14.9 grams, 0.10 mole) were dissolved in methanol (50 ml.). A rapid exothermic reaction ensued and the product precipitated. The reaction temperature was held to 35° C. with ice cooling. After several hours at 25° C., the product was filtered off, washed with methanol, and dried in air. The crude product, melted at ca. 103° C.-110° C. and weighed 22.9 grams (85%). Recrystallizations from hot methanol and from acetone-2-propanol solution (without heating) gave 13.8 grams of α-(nitromethyl)-benzyl dimethyldithiocarbamate melting at 104° C.-108° C. (prior sintering). The infrared spectrum was essentially identical to the spectrum of analytically pure material.

後処理

  1. customA rapid exothermic reaction
  2. customthe product precipitated
  3. customwas held to 35° C. with ice cooling
  4. waitAfter several hours at 25° C.
  5. filtrationthe product was filtered off
  6. washwashed with methanol
  7. customdried in air
  8. customRecrystallizations from hot methanol

出典と根拠

ORDレコード
ord-37533525dc4747488e7748722b12edfd
出典データセット
uspto-grants-1979_04
特許番号
US04148795

関連ノート

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