化工社化工社 化学情報印刷レポート · 研究参考用
Water → HCID 178511480、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Sodium Carbonate | HCID 10340 | — |
| 反応物 | Hydroxyamine hydrochloride | HCID 443297 | — |
| 反応物 | 2-(4-Chlorobenzenesulfonyl)acetonitrile | HCID 735829 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | HCID 178511480 | HCID 178511480 | 70% |
反応手順
50 g. (0.23 mole) of 4-chlorophenylsulfonylacetonitrile were dissolved in 1.5 liters of ethanol and 16 g. (0.23 mole) of hydroxylamine HCl in 150 ml. of water was added to this solution, followed by the addition of 14.4 g. (0.12 mole) of Na2CO3 in 150 ml. of water. This reaction mixture was stirred at room temperature overnight. 58 g. crude product were filtered off; this was recrystallized from about 2.5 liters of ethanol to give 40 g. of the product (70% yield).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04148801 |
| 出典データセット | uspto-grants-1979_04 |
| ORD ID | ord-cfb04106ce044c1b82b83425a88a2633 |
| 出典メモ | uspto-grants-1979_04 |