4-(4-Benzamidobutyl)-5-methylimidazole-2-thione → 4-(4-Benzamidobutyl)-5-methylimidazole
反応式
[C:1]([NH:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14]1[C:18]([CH3:19])=[N:17][C:16](=S)[N:15]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(O)C.[Ni]>[C:1]([NH:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14]1[N:15]=[CH:16][NH:17][C:18]=1[CH3:19])(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1参加物
4
実験手順
4-(4-Benzamidobutyl)-5-methylimidazole-2-thione (4.12 g, 0.01425 mol) in absolute ethanol (80 ml) was desulphrised with Raney nickel (approximately 18 g). Filtration followed by concentration under reduced pressure gave 4-(4-benzamidobutyl)-5-methylimidazole (3.23 g, 88%) m.p. 124°-128°.
後処理
- filtrationFiltration
- concentrationfollowed by concentration under reduced pressure
出典と根拠
- ORDレコード
- ord-6628fa50f0e24f84a78fd204c0358e32
- 出典データセット
- uspto-grants-1979_08
- 特許番号
- US04166184
反応ノート
読み込み中…