Diethyl ethylmalonate → 2-(6-Carboxy-6-phenylhexyl)cyclopent-2-en-1-one

反応式

[C:1]([CH:4]([CH2:16][CH3:17])[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10]1[C:11](=[O:15])[CH2:12][CH2:13][CH:14]=1)([OH:3])=[O:2].[CH2:18]([CH:20](C(OCC)=O)[C:21](OCC)=O)[CH3:19]>>[C:1]([CH:4]([C:16]1[CH:21]=[CH:20][CH:18]=[CH:19][CH:17]=1)[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10]1[C:11](=[O:15])[CH2:12][CH2:13][CH:14]=1)([OH:3])=[O:2]

参加物

反応物 2

HCID 8610Diethyl ethylmalonate

HCID 217678162-(6-Carboxyoctyl)-2-cyclopentenone

生成物 1

HCID 217678182-(6-Carboxy-6-phenylhexyl)cyclopent-2-en-1-one

実験手順

This cyclopentenone is prepared by the procedure described in Belgium Pat. No. 786,215 (Jan. 15, 1973) for the preparation of 2-(6-carboxyoctyl)cyclopent-2-en-1-one by substituting diethyl phenylmalonate for diethyl ethylmalonate.

出典と根拠

ORDレコード: ord-fa98311fb6964404a55cc3e5939920a2
出典データセット: uspto-grants-1979_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04152524

反応ノート

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