alpha,alpha-Bis(p-chlorophenyl)-1-(methoxymethyl)imidazole-2-methanol → Bis-(4-chloro-phenyl)-(1H-imidazol-2-yl)-methanol

HRID 261938

反応式

HRID 261938 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:18]2[CH:23]=[CH:22][C:21]([Cl:24])=[CH:20][CH:19]=2)([C:10]2[N:11](COC)[CH:12]=[CH:13][N:14]=2)[OH:9])=[CH:4][CH:3]=1.C(OCN1C=CN=C1C(C1C=CC(Cl)=CC=1)(C1C=CC=CC=1)O)C1C=CC=CC=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([C:18]2[CH:23]=[CH:22][C:21]([Cl:24])=[CH:20][CH:19]=2)([C:10]2[NH:14][CH:13]=[CH:12][N:11]=2)[OH:9])=[CH:6][CH:7]=1

参加物

3

反応物 2

HCID 12433908alpha,alpha-Bis(p-chlorophenyl)-1-(methoxymethyl)imidazole-2-methanolHCID 124339151-[(Benzyloxy)methyl]-alpha-(p-chlorophenyl)-alpha-phenylimidazole-2-methanol

生成物 1

HCID 12433870Bis-(4-chloro-phenyl)-(1H-imidazol-2-yl)-methanol

実験手順

Using the procedure described in Example VIC but substituting an equivalent amount of α,α-bis(p-chlorophenyl)-1-(methoxymethyl)imidazole-2-methanol for the 1-[(benzyloxy)methyl]-α-(p-chlorophenyl)-α-phenylimidazole-2-methanol, α,α-bis(p-chlorophenyl)imidazole-2-methanol was obtained. Melting point of the product was 195°-197° C.

出典と根拠

ORDレコード
ord-6e743dc9e02f4c939693f55e79f1055f
出典データセット
uspto-grants-1979_05
特許番号
US04152441

関連ノート

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