関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Ethanol | HCID 702 | — |
| 反応物 | Cypenamine Hydrochloride | HCID 21785 | — |
| 生成物 | 5-Methyl-2-[(2-phenylcyclopentyl)imino]pyrrolidine hydrochloride | HCID 135848433 | — |
反応手順
A slurry of 3.0 g (0.0152 mole) of powdered 2-phenylcyclopentylamine hydrochloride and 3 ml of 5,O-dimethylbutyrolactim is allowed to stand at room temperature for 6 days with occasional stirring during which time sufficient ethanol is added to maintain the slurry. The slurry is then cooled to -20° C., and after about four hours a precipitate forms. The precipitate is collected and recrystallized several times from acetone-methanol to give 5-methyl-2-[(2-phenylcyclopentyl)imino]pyrrolidine hydrochloride, M.P. 175°-178° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04153235 |
|---|
| 出典データセット | uspto-grants-1979_05 |
|---|
| ORD ID | ord-fbaa78cfa3df4aa1a397e608f22bf25b |
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| 出典メモ | uspto-grants-1979_05 |
|---|
