Cypenamine Hydrochloride → HCID 178477936、化合物

HRID 262008

反応式

HRID 262008 の反応式
[ClH:1].[C:2]1([CH:8]2[CH2:12][CH2:11][CH2:10][CH:9]2[NH2:13])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.CO[C:16]1[CH2:17][CH2:18][CH2:19][N:20]=1>CCOCC>[ClH:1].[C:2]1([CH:8]2[CH2:12][CH2:11][CH2:10][CH:9]2[N:13]=[C:16]2[CH2:17][CH2:18][CH2:19][NH:20]2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 21785Cypenamine HydrochlorideHCID 3534432-Methoxy-1-Pyrroline

生成物 1

HCID 178477936HCID 178477936、化合物

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

A slurry of 3.0 g (0.0152 mole) of powdered 2-phenylcyclopentylamine hydrochloride and 3 ml of O-methylbutyrolactim is allowed to stand at room temperature with occasional stirring for 6 days after which the material is covered with absolute ether. The solution is allowed to stand at room temperature for an additional 6 days. A precipitate forms which is collected and recrystallized from acetone-methanol and dried to give 2-[(2-phenylcyclopentyl)imino]pyrrolidine hydrochloride, M.P. 155°-158° C.

後処理

  1. customto stand at room temperature
  2. waitto stand at room temperature for an additional 6 days
  3. customA precipitate forms which is collected
  4. customrecrystallized from acetone-methanol
  5. customdried

出典と根拠

ORDレコード
ord-29b0892790ac4c81802d0641a236431b
出典データセット
uspto-grants-1979_05
特許番号
US04153235

関連ノート

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