Hydrogen Peroxide → 3-Amino-5-phenyl-thiazolo-(4,5-c)-isothiazole
反応式
OO.[C:3]1([C:9]2[S:10][C:11]([C:15](=[S:17])[NH2:16])=[C:12]([NH2:14])[N:13]=2)[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1>CO>[NH2:16][C:15]1[S:17][N:14]=[C:12]2[N:13]=[C:9]([C:3]3[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=3)[S:10][C:11]=12参加物
4
反応条件
- 温度
- 22 °C
実験手順
7 parts of 30 percent strength by weight hydrogen peroxide are added to 12.8 parts of 2-phenyl-4-amino-5-thiocarbamoylthiazole in 150 parts of methanol. The mixture is stirred for 12 hours at 22° C. and the product is then filtered off. 7.9 parts of 3-amino-5-phenyl-thiazolo-(4,5-c)-isothiazole (62% of theory) of melting point 176°-179° C. are obtained.
後処理
- filtrationthe product is then filtered off
出典と根拠
- ORDレコード
- ord-051bc14fa00b4a1c9af80e707cbbdeb9
- 出典データセット
- uspto-grants-1979_05
- 特許番号
- US04153607
反応ノート
読み込み中…