Toluene → 1,3-Bis(methoxymethyl)urea

反応式

CC1(C)CC(NCC[C:11]([NH:13]N)=[O:12])CC(C)(C)N1.[CH3:18][O:19][CH2:20][N:21]=[C:22]=[O:23].[C:24]1(C)C=CC=CC=1>>[CH3:18][O:19][CH2:20][NH:21][C:22](=[O:23])[NH:13][CH2:11][O:12][CH3:24]

参加物

反応物 3

HCID 1140Toluene

HCID 62609Methoxymethyl isocyanate

HCID 19609562beta-(2,2,6,6-Tetramethylpiperidine-4-yl)amino-propionic acid hydrazide

生成物 1

HCID 88321,3-Bis(methoxymethyl)urea

反応条件

温度: 25 °C

実験手順

36.3 parts of β-(2,2,6,6-tetramethylpiperidine-4-yl)amino-propionic acid hydrazide are dissolved in 100 parts of toluene, followed by the dropwise addition of 28.2 parts of 93% methoxymethyl isocyanate. After stirring for 1 hour at 25° C., the deposit is filtered off under suction. The filter residue is stirred with 300 parts of petroleum ether and refiltered under suction. 48 parts of colourless crystals melting at 62° to 65° C. are left after drying.