Toluene → 1,3-Bis(methoxymethyl)urea

HRID 262047

反応式

HRID 262047 の反応式
CC1(C)CC(NCC[C:11]([NH:13]N)=[O:12])CC(C)(C)N1.[CH3:18][O:19][CH2:20][N:21]=[C:22]=[O:23].[C:24]1(C)C=CC=CC=1>>[CH3:18][O:19][CH2:20][NH:21][C:22](=[O:23])[NH:13][CH2:11][O:12][CH3:24]

参加物

4

反応物 3

HCID 1140TolueneHCID 62609Methoxymethyl isocyanateHCID 19609562HCID 19609562、化合物

生成物 1

HCID 88321,3-Bis(methoxymethyl)urea

反応条件

温度
25 °C

実験手順

36.3 parts of β-(2,2,6,6-tetramethylpiperidine-4-yl)amino-propionic acid hydrazide are dissolved in 100 parts of toluene, followed by the dropwise addition of 28.2 parts of 93% methoxymethyl isocyanate. After stirring for 1 hour at 25° C., the deposit is filtered off under suction. The filter residue is stirred with 300 parts of petroleum ether and refiltered under suction. 48 parts of colourless crystals melting at 62° to 65° C. are left after drying.

後処理

  1. filtrationthe deposit is filtered off under suction
  2. stirringThe filter residue is stirred with 300 parts of petroleum ether
  3. wait48 parts of colourless crystals melting at 62° to 65° C. are left
  4. customafter drying

出典と根拠

ORDレコード
ord-8705d7da868f4f5c8106314eac885c3d
出典データセット
uspto-grants-1979_05
特許番号
US04153596

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