化工社化工社 化学情報印刷レポート · 研究参考用
Water → 7-Bromo-5-methyl-3-phenylbenzofuran
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | 2-(2-Bromo-4-methylphenoxy)acetophenone | HCID 4077236 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 生成物 | 7-Bromo-5-methyl-3-phenylbenzofuran | HCID 21319928 | — |
反応手順
A mixture of 700 g. of polyphosphoric acid and 100 g. of α-(2-bromo-4-methylphenoxy)acetophenone is heated at 80°-90° C. for two hours, then poured into two liters of water with stirring. Chloroform (1 liter) is added, and the phases are separated. The organic layer is washed with water, dried, then evaporated to provide 7-bromo-5-methyl-3-phenylbenzofuran as a brown oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04153619 |
| 出典データセット | uspto-grants-1979_05 |
| ORD ID | ord-8e550f305de947eaa87715bf888aacd9 |
| 出典メモ | uspto-grants-1979_05 |