2-[(2-Aminoethyl)thiomethyl]pyrazine → HCID 178512220、化合物

反応式

[NH2:1][CH2:2][CH2:3][S:4][CH2:5][C:6]1[CH:11]=[N:10][CH:9]=[CH:8][N:7]=1.CS[C:14](=[NH:19])[NH:15][N+:16]([O-:18])=[O:17]>>[N+:16]([NH:15][C:14]([NH:1][CH2:2][CH2:3][S:4][CH2:5][C:6]1[CH:11]=[N:10][CH:9]=[CH:8][N:7]=1)=[NH:19])([O-:18])=[O:17]

参加物

反応物 2

HCID 129234132-[(2-Aminoethyl)thiomethyl]pyrazine

HCID 135927615N-Nitro-S-methylisothiourea

生成物 1

HCID 178512220HCID 178512220、化合物

実験手順

Reaction of 2-[(2-aminoethyl)thiomethyl]pyrazine with S-methyl-N-nitroisothiourea by the procedure of Example 2(ii) gives N-nitro-N'-[2-(2-pyrazinylmethylthio)-ethyl]guanidine. Similarly by the procedure of Example 2 (iii), there is prepared N-methyl-N'-nitro-N"-[2-(2-pyrazinylmethylthio)ethyl]guanidine.

出典と根拠

ORDレコード: ord-cb06e075821942239b3676f075d5948a
出典データセット: uspto-grants-1979_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04154844

反応ノート

読み込み中…