1-(4-bromophenyl)-4,5-dihydro-1H-pyrazol-3-amine → 1-(4-Bromophenyl)-1H-pyrazol-3-amine

HRID 26275ノート

反応式

HRID 26275 の反応式
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH2:12][CH2:11][C:10]([NH2:13])=[N:9]2)=[CH:4][CH:3]=1>C(O)C.Cl[Cu]>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([N:8]2[CH:12]=[CH:11][C:10]([NH2:13])=[N:9]2)=[CH:6][CH:7]=1

参加物

4

反応物 1

HCID 135631261-(4-bromophenyl)-4,5-dihydro-1H-pyrazol-3-amine

生成物 1

HCID 234642851-(4-Bromophenyl)-1H-pyrazol-3-amine収率 50.5%

試薬・触媒・溶媒 2

HCID 62652Cuprous chloride触媒HCID 702Ethanol溶媒

実験手順

In the same apparatus and following the same modalities as in Example 1, 1 g (0.00416 mole) of 1-(p-bromophenyl)-3-amino-2-pyrazoline was suspended in 10 ml of ethanol with addition of 0.04 g (0.0004 mole) of CuCl and of 0.013 g (0.0002 mole) of Cu, under an oxygen head. Oxidation was concluded after about 3 hours. The oxidized product was recovered as in Example 1, thus obtaining 0.5 g of 1-(p-bromophenyl)-3-aminopyrazole, of melting point 122°-123° C.

後処理

  1. customThe oxidized product was recovered as in Example 1

出典と根拠

ORDレコード
ord-99aa943ace1b4b17bfe66f6523417a29
出典データセット
uspto-grants-1979_04
特許番号
US04149005

反応ノート

読み込み中…