Acetic Anhydride → 3-Methoxycarbonyl-2-benzylidenepropanoic acid

HRID 262750ノート

反応式

HRID 262750 の反応式
[C:1]([CH2:4][C:5](=[CH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[C:6]([OH:8])=[O:7])([OH:3])=[O:2].[C:16](OC(=O)C)(=O)C>>[CH3:16][O:2][C:1]([CH2:4][C:5](=[CH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[C:6]([OH:8])=[O:7])=[O:3]

参加物

3

反応物 2

HCID 7918Acetic AnhydrideHCID 2229982-(Phenylmethylene)butanedioic acid

生成物 1

HCID 541581613-Methoxycarbonyl-2-benzylidenepropanoic acid

実験手順

2-Carboxymethyl-3-phenylpropenoic acid (4.1 g.) and acetic anhydride (9 ml.) are heated in the steam bath for 70 minutes. The mixture is concentrated to dryness and the residue triturated with ether, yield 3.6 g. This anhydride is dissolved in 7 ml. of methanol and heated in the steam bath for 1 hour.

後処理

  1. concentrationThe mixture is concentrated to dryness
  2. customthe residue triturated with ether, yield 3.6 g
  3. dissolutionThis anhydride is dissolved in 7 ml
  4. temperatureof methanol and heated in the steam bath for 1 hour

出典と根拠

ORDレコード
ord-03ac42385c7444d6bceab2c91b25f64c
出典データセット
uspto-grants-1979_05
特許番号
US04154937

反応ノート

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