関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Pyridine | HCID 1049 | — |
| 反応物 | Phenoxyacetyl chloride | HCID 69703 | — |
| 反応物 | Rac. 5-(2,6,6-trimethyl-3-oxo-4-hydroxy-cyclohex-1-en-1-yl)-3-methyl-penta-2,4-dien-1-al | HCID 73769876 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | 5-[2,6,6-trimethyl-3-oxo-4(S)-(phenoxyacetoxy)-cyclohex-1-en-1-yl]-3-methyl-penta-2,4-dien-1-al | HCID 53795135 | — |
反応手順
14 g of the hydroxyketoaldehyde of formula XIII obtained in Example 26 are dissolved in 200 ml of diethyl ether. 20 ml of pyridine are added to the solution at 0° C. and 12 g of phenoxyacetic acid chloride are then added dropwise. The mixture is stirred for 2 hours at 0° C. and then poured into water and extracted with diethyl ether. The 5-[2,6,6-trimethyl-3-oxo-4(S)-(phenoxyacetoxy)-cyclohex-1-en-1-yl]-3-methyl-penta-2,4-dien-1-al (IIA) is isolated from the ether extract.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04156090 |
|---|
| 出典データセット | uspto-grants-1979_05 |
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| ORD ID | ord-afd8878daa1a4d32ae01c955d8fed9e6 |
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| 出典メモ | uspto-grants-1979_05 |
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