tert-Butyl bromoacetate → HCID 10739587、化合物

反応式

[CH:1]([C@H:4]1[CH2:8][O:7][C:6](=[O:9])[N:5]1[C:10](=[O:20])[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19])([CH3:3])[CH3:2].Br[CH2:22][C:23]([O:25][C:26]([CH3:29])([CH3:28])[CH3:27])=[O:24]>>[CH:1]([C@H:4]1[CH2:8][O:7][C:6](=[O:9])[N:5]1[C:10](=[O:20])[C@@H:11]([CH2:22][C:23]([O:25][C:26]([CH3:29])([CH3:28])[CH3:27])=[O:24])[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19])([CH3:3])[CH3:2]

参加物

反応物 2

HCID 79177tert-Butyl bromoacetate

HCID 107554324-(S)-Isopropyl-3-(1-oxodecyl)-2-oxazolidinone

生成物 1

HCID 10739587HCID 10739587、化合物

実験手順

Following the procedure described in Referential Example 4, but using 4-(S)-isopropyl-3-(1-oxodecyl)-2-oxazolidinone (9.85 g), prepared in Referential Example 49, and tert-butyl bromoacetate (25.4 ml) as starting materials, the desired compound (9.17 g) having a m.p. of 58°-59° C. was obtained.

出典と根拠

ORDレコード: ord-79066269c56a41678ef08897c30c7702
出典データセット: uspto-grants-1997_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05643908

反応ノート

読み込み中…