3,4-Diethoxybenzene-1-carbothioamide → 2-(3,4-Diethoxyphenyl)-4-(4-carboxy-2-pyrrolyl)thiazole
反応式
C([O:3][C:4]([C:6]1[CH:7]=[C:8]([C:11](=O)[CH2:12]Br)[NH:9][CH:10]=1)=[O:5])C.[CH2:15]([O:17][C:18]1[CH:19]=[C:20]([CH:24]=[CH:25][C:26]=1[O:27][CH2:28][CH3:29])[C:21]([NH2:23])=[S:22])[CH3:16]>>[CH2:15]([O:17][C:18]1[CH:19]=[C:20]([C:21]2[S:22][CH:12]=[C:11]([C:8]3[NH:9][CH:10]=[C:6]([C:4]([OH:3])=[O:5])[CH:7]=3)[N:23]=2)[CH:24]=[CH:25][C:26]=1[O:27][CH2:28][CH3:29])[CH3:16]参加物
3
実験手順
4-Ethoxycarbonyl-2-(α-bromoacetyl)pyrrole and 3,4- diethoxythiobenzamide were subjected to the same reaction as in Example 1 and then to the same hydrolysis as in Example 147 to obtain 2-(3,4-diethoxyphenyl)-4-(4-carboxy-2-pyrrolyl)thiazole.
後処理
- customto the same hydrolysis as in Example 147
出典と根拠
- ORDレコード
- ord-675af471fcd04ccea61e97cdaedd94b2
- 出典データセット
- uspto-grants-1997_07