Acetic Acid → Methyl 3-hydroxy-2-methyl-5-nitro-3-indenylacetate

HRID 263619ノート

反応式

HRID 263619 の反応式
[CH3:1][CH:2]1[CH2:10][C:9]2[C:4](=[CH:5][C:6]([N+:11]([O-:13])=[O:12])=[CH:7][CH:8]=2)[C:3]1=[O:14].[CH3:15][O:16][C:17]1[CH:25]=C2C(CC(C)C2=O)=CC=1.C([OH:30])C.C(O)(=O)C>O>[OH:14][C:3]1([CH2:25][C:17]([O:16][CH3:15])=[O:30])[C:4]2[C:9](=[CH:8][CH:7]=[C:6]([N+:11]([O-:13])=[O:12])[CH:5]=2)[CH:10]=[C:2]1[CH3:1]

参加物

6

反応物 4

HCID 176Acetic AcidHCID 702EthanolHCID 2311786-Methoxy-2-methyl-2,3-dihydro-1H-inden-1-oneHCID 218405862-Methyl-6-nitro-1-indanone

生成物 1

HCID 53908697Methyl 3-hydroxy-2-methyl-5-nitro-3-indenylacetate

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

The procedure of Example 1C is followed using 2-methyl-6-nitro indanone in equivalent quantities in place of 6-methoxy-2-methyl-indanone used therein. After the mixture is condensed, 30 ml. of ethanol and 50 ml. of acetic acid are added. The mixture is then poured into 700 ml. of water. Extraction with ether gives methyl 3-hydroxy-2-methyl-5-nitro-3-indenylacetate.

後処理

  1. customcondensed, 30 ml
  2. additionThe mixture is then poured into 700 ml
  3. extractionExtraction with ether

出典と根拠

ORDレコード
ord-492f7d423e534647afa22075b85263ca
出典データセット
uspto-grants-1997_07
特許番号
US05643959

反応ノート

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