1,1'-(Diazomethylene)bis(benzene) → HCID 18705268、化合物

HRID 263681

反応式

HRID 263681 の反応式
[O:1]=[C:2]1[O:6][CH:5]([C:7]([OH:9])=[O:8])[CH:4]([C:10]([OH:12])=[O:11])[CH2:3]1.[C:13]1([C:19]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[N+]=[N-])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>CC(C)=O>[C:13]1([CH:19]([C:22]2[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=2)[O:8][C:7]([CH:5]2[CH:4]([C:10]([OH:12])=[O:11])[CH2:3][C:2](=[O:1])[O:6]2)=[O:9])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

参加物

4

反応物 2

HCID 612301,1'-(Diazomethylene)bis(benzene)HCID 98259Tetrahydro-5-oxofuran-2,3-dicarboxylic acid

生成物 1

HCID 18705268HCID 18705268、化合物収率 102.2%

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

262 mg of (2RS,3SR)-5-oxotetrahydrofuran-2,3-dicarboxylic acid was dissolved in 5 ml of acetone, and 91 mg of diphenyldiazomethane was added thereto, followed by stirring at room temperature for 20 minutes. The reaction solution was evaporated to dryness under reduced pressure. The residue was purified by silica gel column chromatography (chloroform/methanol=100/1→10/1) to obtain 163 mg of the above-identified compound as white powder.

後処理

  1. customThe reaction solution was evaporated to dryness under reduced pressure
  2. customThe residue was purified by silica gel column chromatography (chloroform/methanol=100/1→10/1)

出典と根拠

ORDレコード
ord-d3523c644e1a4fe9adc49a880e321cd1
出典データセット
uspto-grants-1997_07
特許番号
US05643958

関連ノート

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