2-benzyl 3-tert-butyl (2RS,3RS)-5-oxotetrahydrofuran-2,3-dicarboxylate → HCID 18705233、化合物

HRID 263693

反応式

HRID 263693 の反応式
[O:1]=[C:2]1[O:6][CH:5]([C:7]([O:9]CC2C=CC=CC=2)=[O:8])[CH:4]([C:17]([O:19][C:20]([CH3:23])([CH3:22])[CH3:21])=[O:18])[CH2:3]1>C(OCC)(=O)C.[C].[Pd]>[C:20]([O:19][C:17]([CH:4]1[CH2:3][C:2](=[O:1])[O:6][CH:5]1[C:7]([OH:9])=[O:8])=[O:18])([CH3:23])([CH3:21])[CH3:22]

参加物

4

反応物 1

HCID 536709302-benzyl 3-tert-butyl (2RS,3RS)-5-oxotetrahydrofuran-2,3-dicarboxylate

生成物 1

HCID 18705233HCID 18705233、化合物収率 95.9%

試薬・触媒・溶媒 2

HCID 178418390HCID 178418390、化合物触媒HCID 8857Ethyl Acetate溶媒

実験手順

2.70 g of 2-benzyl 3-tert-butyl (2RS,3SR)-5-oxotetrahydrofuran-2,3-dicarboxylate was dissolved in 30 ml of ethyl acetate, and 300 mg of a 10% palladium-carbon catalyst was added thereto, followed by catalytic reduction for 3 hours at room temperature under hydrogen atmospheric pressure. The catalyst was filtered off, and the filtrate was evaporated to dryness under reduced pressure to obtain 1.86 g of the above-identified compound as white solid.

後処理

  1. filtrationThe catalyst was filtered off
  2. customthe filtrate was evaporated to dryness under reduced pressure

出典と根拠

ORDレコード
ord-fc8863470cf74fe1bf5eea26d6d3a448
出典データセット
uspto-grants-1997_07
特許番号
US05643958

関連ノート

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