Sodium borohydride → 9-Hydroxy-9H-indeno[1,2-b]pyrazin-3(4H)-one

関与物質

役割	名称	HCID	仕込み量
反応物	Sodium borohydride	HCID 4311764	—
反応物	9H-Indeno[1,2-b]pyrazine-3,9(4H)-dione	HCID 19035976	—
生成物	9-Hydroxy-9H-indeno[1,2-b]pyrazin-3(4H)-one	HCID 19035984	104.7%

反応手順

9H-Indeno[1,2-b]pyrazine-3,9(4H)-dione (5.0 g, 25.23 mmol) was reduced with sodium borohydride (1.72 g, 45.5 mmol) as described in example 11. Yield 5.29 g (96%) of the title compound. M.p. 251°-253° C. 1H-NMR (DMSO-d6, δ): 5.32 (d, 1H), 5.92 (d, 1H), 7.47 (m, 2H), 7.64 (m, 1H), 7.8 (m, 1H) 7.9 (s, 1H), 12.5 (s, 1H).

情報源と証拠

DOI	10.6084/m9.figshare.5104873.v1
特許番号	US05646146
出典データセット	uspto-grants-1997_07
ORD ID	ord-62b53a716dd04e5988591a61f9c96b2f
出典メモ	uspto-grants-1997_07