1-(2,6-Dibromophenyl)thiourea → 2,6-Dibromophenyl isothiocyanate
反応式
[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Br:8])[C:3]=1[NH:9][C:10](N)=[S:11]>ClC1C=CC=CC=1>[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Br:8])[C:3]=1[N:9]=[C:10]=[S:11]参加物
3
実験手順
A suspension of 101 g. (0.326 mole) of 1-(2,6-dibromophenyl)thiourea in 1 l. of chlorobenzene was stirred and refluxed 20 hours, and the resulting solution was filtered and evaporated. The tan solid obtained was triturated with boiling petroleum ether and filtered. On cooling, the filtrate deposited 63.4 g. of yellow needles of 2,6-dibromophenylisothiocyanate, m.p. 63°-65°. A portion was recrystallized from ether-petroleum ether to give the analytical sample, m.p. 65°-66°.
後処理
- additionA suspension of 101 g
- temperaturerefluxed 20 hours
- filtrationthe resulting solution was filtered
- customevaporated
- customThe tan solid obtained
- customwas triturated with boiling petroleum ether
- filtrationfiltered
- temperatureOn cooling
- customA portion was recrystallized from ether-petroleum ether
- customto give the analytical sample, m.p. 65°-66°
出典と根拠
- ORDレコード
- ord-66d87c969fa247bb8ecb1ca2fb9d3309
- 出典データセット
- uspto-grants-1979_04
- 特許番号
- US04150138
反応ノート
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