Hippuric Acid → Azlactone
反応式
[C:1]([OH:13])(=[O:12])[CH2:2][NH:3][C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)=O.C(OC(=O)C)(=O)C>C1(C)C=CC=CC=1>[C:6]1([C:4]2[O:13][C:1](=[O:12])[CH2:2][N:3]=2)[CH:7]=[CH:8][CH:9]=[CH:10][CH:11]=1参加物
4
反応条件
- 温度
- 90 °C
実験手順
23.3 gm (0.13 mol) of hippuric acid, 93.05 gm of acetic anhydride, and 50 ml of toluene were charged into a 500 ml eggplant-type flask, and heated on an oil bath at a temperature of 90° C. for 10 minutes to dissolution, followed by immediate quenching the resultant solution. The produced liquid was kept at -20° C. on a dry ice-methanol bath.
後処理
- customby immediate quenching the resultant solution
- customThe produced liquid was kept at -20° C. on a dry ice-methanol bath
出典と根拠
- ORDレコード
- ord-2db5e132f46d465d95caebbd575099ab
- 出典データセット
- uspto-grants-1997_07
- 特許番号
- US05646291
反応ノート
読み込み中…