化工社化工社 化学情報印刷レポート · 研究参考用
3-methylsulfonyl-11H-s-triazolo[3,4-b][3]benzazapine → 3-ethoxy-11H-s-triazolo[3,4-b][3]benzazepine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-methylsulfonyl-11H-s-triazolo[3,4-b][3]benzazapine | HCID 21323525 | — |
| 反応物 | 3-methylsulfinyl-11H-s-triazolo[3,4-b][3]benzazepine | HCID 21323529 | — |
| 反応物 | Ethanol sodium ethoxide | HCID 23706232 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 3-ethoxy-11H-s-triazolo[3,4-b][3]benzazepine | HCID 21323356 | — |
反応手順
By a procedure similar to that described in Example 35, 0.245 g of 3-methylsulfinyl-11H-s-triazolo [3,4-b][3]benzazepine, in lieu of 3-methylsulfonyl-11H-s-triazolo[3,4-b][3]benzazepine, was reacted with 1.2 ml of 1 N-sodium ethoxide/ethanol in 2 ml of ethanol to obtain 3-ethoxy-11H-s-triazolo[3,4-b][3]benzazepine as crystals. Recrystallization from acetone yielded colorless needles, melting point 143°-144° C. The infrared absorption spectrum of this product was identical with that of the compound obtained in Example 35.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04150139 |
| 出典データセット | uspto-grants-1979_04 |
| ORD ID | ord-66aacf99ccc542b9aff3e8ef366f46b2 |
| 出典メモ | uspto-grants-1979_04 |