Phenyl isocyanate → N-Phenyl-N'-2-pyridinylurea

HRID 26571ノート

反応式

HRID 26571 の反応式
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][N:3]=1.C([O-])(=O)CCCCCCCCCCC.C([O-])(=O)CCCCCCCCCCC.C([Sn+2]CCCC)CCC.[C:45]1([N:51]=[C:52]=[O:53])[CH:50]=[CH:49][CH:48]=[CH:47][CH:46]=1>C1(C)C=CC=CC=1>[N:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[NH:1][C:52]([NH:51][C:45]1[CH:50]=[CH:49][CH:48]=[CH:47][CH:46]=1)=[O:53]

参加物

4

反応物 2

HCID 7672Phenyl isocyanateHCID 867364832-Aminopyridine dibutyl tin dilaurate

生成物 1

HCID 221427N-Phenyl-N'-2-pyridinylurea

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

29.04 g of a catalyst mixture of 2-aminopyridine/dibutyl tin dilaurate (molar ratio 1:1) in 37 ml of toluene are reacted with 4.76 g of phenyl isocyanate at room temperature. Petroleum ether is added to the resulting suspension after 11/2 hours and the colorless precipitate is suction filtered. 7 g of N-(2-pyridyl)-N'-phenyl urea, m.p. 186°-188° C. are isolated.

後処理

  1. filtrationfiltered

出典と根拠

ORDレコード
ord-a608c8292b2840b09fce86644623fcb1
出典データセット
uspto-grants-1979_04
特許番号
US04150212

反応ノート

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