HCID 54677766、化合物 → 4-Hydroxy-5,6,7,8-tetrahydroquinolin-2(1H)-one
反応式
[OH:1][C:2]1[C:11]2[CH2:10][CH2:9][CH2:8][CH2:7][C:6]=2[NH:5][C:4](=[O:12])[C:3]=1C(OC)=O.OC1C2CCCCC=2NC(=O)C=1C(O)=O>>[OH:1][C:2]1[C:11]2[CH2:10][CH2:9][CH2:8][CH2:7][C:6]=2[NH:5][C:4](=[O:12])[CH:3]=1参加物
3
実験手順
Using the general method of Example 1 Part E, a mixture of methyl 1,2,5,6,7,8-hexahydro-4-hydroxy-2-oxoquinoline-3-carboxylate and 1,2,5,6,7,8-hexahydro-4-hydroxy-2-oxoquinoline-3-carboxylic acid (1.92 g total) was hydrolyzed and decarboxylated to provide 1.38 g of 5,6,7,8-tetrahydro-4-hydroxy-2(1H)-quinolinone as a white solid, m.p. >300° C.
出典と根拠
- ORDレコード
- ord-2b56d201d1a948b7b00c3f30c1e4bc7a
- 出典データセット
- uspto-grants-1997_07
- 特許番号
- US05648516
反応ノート
読み込み中…