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Acetonitrile → 2-Methylquinazoline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetonitrile | HCID 6342 | — |
| 反応物 | 2-Aminobenzophenone | HCID 76080 | — |
| 生成物 | 2-Methylquinazoline | HCID 588987 | — |
反応手順
In this method, the 2-aminobenzophenone derivative (IV) is reacted with acetonitrile to give the 2-methylquinazoline derivative (IX). The compound (IX) is subjected to bromination to give the 2-bromomethylquinazoline derivative (II-4). The reaction of the compound (IV) with acetonitrile can be carried out according to the same manner as that of Method D. The bromination of the compound (IX) can be carried out according to the same manner as that of the bromination of the compound (VII) in Method C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05650410 |
| 出典データセット | uspto-grants-1997_07 |
| ORD ID | ord-c9dd40a373ab4a39b3ccca2a27630ca6 |
| 出典メモ | uspto-grants-1997_07 |