Benzenamine, 2-chloro-5-(trifluoromethyl)- → N-(2,2-dicyanovinyl)-2-chloro-5-trifluoromethylaniline

HRID 26707

反応式

HRID 26707 の反応式
[Cl:1][C:2]1[CH:8]=[CH:7][C:6]([C:9]([F:12])([F:11])[F:10])=[CH:5][C:3]=1[NH2:4].C(O[CH:16]=[C:17]([C:20]#[N:21])[C:18]#[N:19])C>C(O)C>[C:18]([C:17]([C:20]#[N:21])=[CH:16][NH:4][C:3]1[CH:5]=[C:6]([C:9]([F:10])([F:11])[F:12])[CH:7]=[CH:8][C:2]=1[Cl:1])#[N:19]

参加物

4

反応物 2

HCID 8475Benzenamine, 2-chloro-5-(trifluoromethyl)-HCID 671522-(Ethoxymethylene)propanedinitrile

生成物 1

HCID 21322397N-(2,2-dicyanovinyl)-2-chloro-5-trifluoromethylaniline収率 70%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

19.6 Parts of 2-chloro-5-trifluoromethyl-aniline and 12.2 parts of ethoxymethylenemalononitrile are dissolved in 125 parts of ethanol and the mixture is refluxed for 48 hours. After cooling, the precipitated product is collected by filtration and washed with ethanol. Recrystallisation from ethanol affords the above product with a melting point of 166°-169° C. and in a 70% yield.

後処理

  1. temperaturethe mixture is refluxed for 48 hours
  2. temperatureAfter cooling
  3. filtrationthe precipitated product is collected by filtration
  4. washwashed with ethanol
  5. customRecrystallisation from ethanol
  6. customaffords the above product with a melting point of 166°-169° C.

出典と根拠

ORDレコード
ord-bc92207860594f63ba30a4e98edc8c79
出典データセット
uspto-grants-1979_04
特許番号
US04151298

関連ノート

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