関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Dabco | HCID 9237 | — |
| 反応物 | Methyl Isocyanate | HCID 12228 | — |
| 反応物 | N,N-dimethyl-2-hydroxyimino-3-methoxyiminobutyramide | HCID 136099002 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | N,N-dimethyl-3-methoxyimino-2-[(methylcarbamoyl)oximino]butyramide | HCID 53959603 | — |
反応手順
A mixture of 34 parts of N,N-dimethyl-2-hydroxyimino-3-methoxyiminobutyramide, 350 parts of methylene chloride, 13 parts of methyl isocyanate and one-tenth part triethylenediamine was stirred at 25° C. for 3 hours and then refluxed for 1 hour. The solvent was removed by stripping under reduced pressure (15 mm.) at 50° bath temperature, thereby affording the solid crude product. Recrystallization from a benzene-acetonitrile mixture gave 32 parts of N,N-dimethyl-3-methoxyimino-2-[(methylcarbamoyl)oximino]butyramide, m.p. 172°-173° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US04151296 |
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| 出典データセット | uspto-grants-1979_04 |
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| ORD ID | ord-515cd4a944c94100a0ce420c1a056260 |
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| 出典メモ | uspto-grants-1979_04 |
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