化工社化工社 化学情報印刷レポート · 研究参考用
4-Hydroxybenzoic Acid → Benzoic acid, 4-(acetyloxy)-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Hydroxybenzoic Acid | HCID 135 | — |
| 反応物 | Acetyl chloride | HCID 6367 | — |
| 溶媒 | Benzene | HCID 241 | — |
| 生成物 | Benzoic acid, 4-(acetyloxy)- | HCID 16865 | — |
反応手順
A solution of 20 g. of 4-hydroxybenzoic acid in 200 ml. of benzene and 40 ml. of acetyl chloride is refluxed for 3 hours. Solvent and excess acetyl chloride are evaporated. The mixture is dissolved in methanol (150 ml.) and water (20 ml.) added; after 15 minutes, addition of more water results in the precipitation of 4-acetoxy benzoic acid, m.p. 192°-193° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04151297 |
| 出典データセット | uspto-grants-1979_04 |
| ORD ID | ord-97e6103d3157480888b34d018a955edc |
| 出典メモ | uspto-grants-1979_04 |