化工社化工社 化学情報印刷レポート · 研究参考用
Toluene → Ethyl 4-(2-pyrimidinylimino)-1-piperidinecarboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Toluene | HCID 1140 | — |
| 反応物 | 2-Aminopyrimidine | HCID 7978 | — |
| 反応物 | Ethyl 4-oxo-1-piperidinecarboxylate | HCID 34767 | — |
| 触媒 | Acetic Acid | HCID 176 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | Ethyl 4-(2-pyrimidinylimino)-1-piperidinecarboxylate | HCID 21460901 | — |
反応手順
A mixture of 34 parts of ethyl 4-oxo-1-piperidinecarboxylate, 20 parts of 2-pyrimidinamine, 8 drops of acetic acid and 90 parts of methylbenzene is stirred and refluxed for 28 hours with water-separator. The reaction mixture is evaporated, yielding 50 parts of ethyl 4-(2-pyrimidinylimino)-1-piperidinecarboxylate as a residue.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04151286 |
| 出典データセット | uspto-grants-1979_04 |
| ORD ID | ord-703b2da5f9a44fb3a4000f8a8b5801ac |
| 出典メモ | uspto-grants-1979_04 |