Ethyl 2'-chloro-4-biphenylylglyoxylate → Ethyl 2'-chloro-4-biphenylylglycolate

HRID 267371ノート

反応式

HRID 267371 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:13]=[CH:12][C:11]([C:14](=[O:20])[C:15]([O:17][CH2:18][CH3:19])=[O:16])=[CH:10][CH:9]=1.[H][H]>[Pt]=O>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:13]=[CH:12][C:11]([CH:14]([OH:20])[C:15]([O:17][CH2:18][CH3:19])=[O:16])=[CH:10][CH:9]=1

参加物

4

反応物 2

HCID 21556138Ethyl 2'-chloro-4-biphenylylglyoxylateHCID 178418361HCID 178418361、化合物2 回

生成物 1

HCID 21556089Ethyl 2'-chloro-4-biphenylylglycolate

試薬・触媒・溶媒 1

HCID 82844Platinum oxide (PtO)触媒

実験手順

Into a Paar hydrogenation bottle is added 41.5 g. (0.144 mole) of ethyl 2'-chloro-4-biphenylylglyoxylate, 2 ml. of 0.1 M-ferrous sulfate solution, 220 ml. of isopropionyl and 1.0 g. of 85.1% platinum oxide. The mixture is shaken for 2 hours at room temperature with hydrogen gas until 0.144 mole of hydrogen is absorbed. The catalyst is then filtered off and the solution is evaporated in vacuo and the residue fractionally distilled to obtain ethyl 2'-chloro-4-biphenylylglycolate.

後処理

  1. additionInto a Paar hydrogenation bottle is added 41.5 g
  2. customis absorbed
  3. filtrationThe catalyst is then filtered off
  4. customthe solution is evaporated in vacuo
  5. distillationthe residue fractionally distilled

出典と根拠

ORDレコード
ord-e4821f4c62e54200a7ddafa86f96b818
出典データセット
uspto-grants-1976_03
特許番号
US03941821

反応ノート

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