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2-Nitrobenzaldehyde → 4-(2'-Nitrophenyl)-1,4-dihydropyridine-2,3,5,6-tetracarboxylic acid tetraethyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Nitrobenzaldehyde | HCID 11101 | — |
| 反応物 | Diethyl oxalacetate | HCID 66951 | — |
| 反応物 | Diethyl 2-iminobutanedioate | HCID 18977200 | — |
| 生成物 | 4-(2'-Nitrophenyl)-1,4-dihydropyridine-2,3,5,6-tetracarboxylic acid tetraethyl ester | HCID 86733113 | — |
反応手順
A solution of 7.5 g of o-nitrobenzaldehyde, 9.5 g of oxalacetic acid diethyl ester and 9.4 g of iminosuccinic acid diethyl ester in 30 ccs of alcohol is heated under reflux overnight and subsequently cooled. After filtration, light yellow crystals of melting point 109° (ethanol) are obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US03943140 |
| 出典データセット | uspto-grants-1976_03 |
| ORD ID | ord-1904ade0fa7f41bb8f03cf302d2b098d |
| 出典メモ | uspto-grants-1976_03 |