Potassium Iodide → 1-Iodo-3-methyl-2-nitrobenzene

反応式

NC1C(N)=C(C2C=CC(C)=CC=2)C=CC=1C.N[C:18]1[C:19]([N+:25]([O-:27])=[O:26])=[C:20]([CH3:24])[CH:21]=[CH:22][CH:23]=1.[I-:28].[K+].N(O)=O>>[I:28][C:18]1[C:19]([N+:25]([O-:27])=[O:26])=[C:20]([CH3:24])[CH:21]=[CH:22][CH:23]=1

参加物

反応物 4

HCID 4875Potassium Iodide

HCID 24529Nitrous Acid

HCID 690383-Methyl-2-nitroaniline

HCID 131710095HCID 131710095、化合物

生成物 1

HCID 533387711-Iodo-3-methyl-2-nitrobenzene

実験手順

The diaminodimethylbiphenyl from which the present synthesis is initiated is not commercially available, however, the compound can be prepared by the method reported by Carlin and FOltz wherein aminonitrotoluene is reacted with potassium iodide in the presence of nitrous acid to give iodonitrotoluene. Two moles of the iodonitrotoluene are reacted then in the presence of copper powder to produce dinitrodimethylbiphenyl. Subsequent reduction with hydrogen in the presence of a catalyst produces the corresponding amino compound.