HCID 12923316、化合物 → 2-Methyl-3-tert.-butoxypropan-1-ol

反応式

[C:1]([O:5][CH2:6][CH:7]([CH3:15])[C:8](OC(C)(C)C)=[O:9])([CH3:4])([CH3:3])[CH3:2].[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[C:1]([O:5][CH2:6][CH:7]([CH3:15])[CH2:8][OH:9])([CH3:4])([CH3:3])[CH3:2]

参加物

反応物 2

HCID 12923316HCID 12923316、化合物

HCID 21226445Aluminium lithium hydride

生成物 1

HCID 125367792-Methyl-3-tert.-butoxypropan-1-ol収率 88%

実験手順

Reduction of rac.-tert. butyl 3-tert.butoxy-2-methylpropionate was carried out with lithium aluminum hydride using the procedure described in Example 2. The resulting rac.-3-tert. butoxy-2-methyl-1-propanol was obtained in 88% yield as a colorless liquid. b.p. 70°-72° C. (10 mm Hg.).

出典と根拠

ORDレコード: ord-a8d1eefe462849729dcaa8c3bbabe320
出典データセット: uspto-grants-1979_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04151205

反応ノート

読み込み中…