(R)-(+)-4-tert. butoxy-3-methyl-1butanol p-toluenesulfonate → 4-methylbenzenesulfonic acid;(3R)-3-methyl-4-[(2-methylpropan-2-yl)oxy]butan-1-ol

HRID 26789ノート

反応式

HRID 26789 の反応式
[C:1]([O:5][CH2:6][CH:7]([CH3:11])[CH2:8][CH2:9][OH:10])([CH3:4])([CH3:3])[CH3:2].[C:12]1([CH3:32])[CH:17]=[CH:16][C:15]([S:18]([O:21]CC[C@@H](C)COC(C)(C)C)(=[O:20])=[O:19])=[CH:14][CH:13]=1>>[C:1]([O:5][CH2:6][C@H:7]([CH3:11])[CH2:8][CH2:9][OH:10])([CH3:3])([CH3:4])[CH3:2].[CH3:32][C:12]1[CH:17]=[CH:16][C:15]([S:18]([OH:21])(=[O:20])=[O:19])=[CH:14][CH:13]=1

参加物

3

反応物 2

HCID 131710899(R)-(+)-4-tert. butoxy-3-methyl-1butanol p-toluenesulfonateHCID 1317114874-Tert. butoxy-3-methyl-1-butanol

生成物 1

HCID 867351114-methylbenzenesulfonic acid;(3R)-3-methyl-4-[(2-methylpropan-2-yl)oxy]butan-1-ol収率 90%

実験手順

Using the procedure of Example 8, (R)-(+)-(4-tert. butoxy-3-methyl-1-butanol was converted into (R)-(+)-4-tert. butoxy-3-methyl-1-butanol p-toluenesulfonate which was isolated in 90% yield as a pale yellow oil.

後処理

  1. customwas isolated in 90% yield as a pale yellow oil

出典と根拠

ORDレコード
ord-915076a507e44190bef2743fded600fa
出典データセット
uspto-grants-1979_04
特許番号
US04151205

反応ノート

読み込み中…