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Potassium Carbonate → N-(1,3-dioxolan-5-ylmethyl)-2-methyl-6-methoxyaniline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 4-(Chloromethyl)-1,3-dioxolane | HCID 240153 | — |
| 反応物 | 2-Methoxy-6-methylaniline | HCID 459249 | — |
| 触媒 | Tetraethylammonium Chloride | HCID 5946 | — |
| 生成物 | N-(1,3-dioxolan-5-ylmethyl)-2-methyl-6-methoxyaniline | HCID 21447805 | — |
反応手順
2-Methyl-6-methoxyaniline (0.3 mole), 5-chloromethyl-1,3-dioxolane (0.3 mole), potassium carbonate (0.3 mole) and tetraethylammonium chloride (2 grams) are charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. The reaction mixture is heated at reflux for a period of 4 hours. After this time the mixture is filtered and distilled to yield the desired product N-(1,3-dioxolan-5-ylmethyl)-2-methyl-6-methoxyaniline.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US03946045 |
| 出典データセット | uspto-grants-1976_03 |
| ORD ID | ord-8ddec6bbba5c4402bd66d5f98fa1b0ed |
| 出典メモ | uspto-grants-1976_03 |