4-Methyl-3-nitroaniline → HCID 178428208、化合物

HRID 268274

反応式

HRID 268274 の反応式
[ClH:1].N([C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[C:16]3[N:21]=[CH:20][NH:19][C:17]3=2)[N:12]=[C:11]([CH3:22])[CH:10]=1)C1C=CC=CC=1.[CH3:23][C:24]1[CH:30]=[CH:29][C:27]([NH2:28])=[CH:26][C:25]=1[N+:31]([O-:33])=[O:32]>C(O)C>[ClH:1].[CH3:23][C:24]1[CH:30]=[CH:29][C:27]([NH:28][C:9]2[C:18]3[C:13](=[CH:14][CH:15]=[C:16]4[N:21]=[CH:20][NH:19][C:17]4=3)[N:12]=[C:11]([CH3:22])[CH:10]=2)=[CH:26][C:25]=1[N+:31]([O-:33])=[O:32]

参加物

4

反応物 2

HCID 83904-Methyl-3-nitroanilineHCID 178428198HCID 178428198、化合物

生成物 1

HCID 178428208HCID 178428208、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A mixture of 10.85 g. (0.05 m.) of the compound of Example I, C., 7.6 g. (0.05 m.) of 4-methyl-3-nitroaniline and 500 ml. of ethanol was refluxed overnight. The reaction mixture was concentrated in vacuo to give 38 g. of crude product. It was then dissolved in 6000 ml. of MeOH and filtered hot. The MeOH filtrate was concentrated in vacuo to yield 27 g., m.p. 344°-345°C.

後処理

  1. additionA mixture of 10.85 g
  2. concentrationThe reaction mixture was concentrated in vacuo
  3. customto give 38 g
  4. dissolutionIt was then dissolved in 6000 ml
  5. filtrationof MeOH and filtered hot
  6. concentrationThe MeOH filtrate was concentrated in vacuo
  7. customto yield 27 g

出典と根拠

ORDレコード
ord-5a650ce85fff40e790f052503055eb84
出典データセット
uspto-grants-1976_03
特許番号
US03947434

関連ノート

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