5-Hydroxy-7-[5-(4-Fluorophenyl)-2-Pentyl]-4-(4-Pyridyl)Coumarin → HCID 23878078、化合物

HRID 268445ノート

反応式

HRID 268445 の反応式
[OH:1][C:2]1[CH:11]=[C:10]([CH:12]([CH2:14][CH2:15][CH2:16][C:17]2[CH:22]=[CH:21][C:20]([F:23])=[CH:19][CH:18]=2)[CH3:13])[CH:9]=[C:8]2[C:3]=1[C:4]([C:25]1[CH:30]=[CH:29][N:28]=[CH:27][CH:26]=1)=[CH:5][C:6](=[O:24])[O:7]2>C(O)C>[OH:1][C:2]1[CH:11]=[C:10]([CH:12]([CH2:14][CH2:15][CH2:16][C:17]2[CH:22]=[CH:21][C:20]([F:23])=[CH:19][CH:18]=2)[CH3:13])[CH:9]=[C:8]2[C:3]=1[CH:4]([C:25]1[CH:26]=[CH:27][N:28]=[CH:29][CH:30]=1)[CH2:5][C:6](=[O:24])[O:7]2

参加物

3

反応物 1

HCID 239388075-Hydroxy-7-[5-(4-Fluorophenyl)-2-Pentyl]-4-(4-Pyridyl)Coumarin

生成物 1

HCID 23878078HCID 23878078、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol触媒

実験手順

The coumarin of Example 2 (2.2 g) was hydrogenated in ethanol using 5% palladium on carbon as a catalyst. The resulting oil was purified on a Florisil column, eluting with chloroform to give the desired product.

後処理

  1. customThe resulting oil was purified on a Florisil column
  2. washeluting with chloroform

出典と根拠

ORDレコード
ord-92d95fcff0494625b5e9bbc24178a3e4
出典データセット
uspto-grants-1976_03
特許番号
US03947462

反応ノート

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