化工社化工社 化学情報印刷レポート · 研究参考用
Diboron → (3-Chloro-5-methylpyrazin-2-yl)methanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Diboron | HCID 6328200 | — |
| 反応物 | 3-Chloro-5-methylpyrazine-2-carboxylic acid | HCID 20557998 | — |
| 生成物 | (3-Chloro-5-methylpyrazin-2-yl)methanol | HCID 20557611 | — |
反応手順
Reduction of 3-chloro-5-methyl-2-pyrazinecarboxylic acid (prepared by alkaline hydrolysis of the methyl ester) with diborane gives 3-chloro-2-hydroxymethyl-5-methylpyrazine which, using the above procedure, yields N-methyl-N'-[2-((3-chloro-5-methyl-2-pyrazinyl)methylthio)ethyl]thiourea.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04151288 |
| 出典データセット | uspto-grants-1979_04 |
| ORD ID | ord-324645d3203042189d7320a49ef1caf8 |
| 出典メモ | uspto-grants-1979_04 |