Methyl Isocyanate → N-Methyl-N'-[2-(2-pyrimidylmethylamino)ethyl]urea
反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[N:3][C:2]=1[CH2:7][NH:8][CH2:9][CH2:10][NH2:11].[CH3:12][N:13]=[C:14]=[O:15]>>[CH3:12][NH:13][C:14]([NH:11][CH2:10][CH2:9][NH:8][CH2:7][C:2]1[N:3]=[CH:4][CH:5]=[CH:6][N:1]=1)=[O:15]参加物
3
実験手順
By the procedure of Example 24, N-(2-pyrimidylmethyl)ethylenediamine is reacted with methyl isocyanate to give, after concentrating and separating the residue by column chromatography, the title compound.
後処理
- customto give
- concentrationafter concentrating
- customseparating the residue by column chromatography
出典と根拠
- ORDレコード
- ord-c01fe4e9ffaf4cbeb3133c40c84c98c9
- 出典データセット
- uspto-grants-1979_04
- 特許番号
- US04151288
反応ノート
読み込み中…