Tetrafluoro-m-phenylenediamine dihydrochloride → 4-(4-Amino-3-methylphenylamino)butan-2-ol dihydrochloride

HRID 268569ノート

反応式

HRID 268569 の反応式
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10][CH2:11][CH2:12][CH:13]([OH:15])[CH3:14])=[CH:6][C:5]=1[CH3:16])([O-])=O.C1(N)C(F)=C(F)C(F)=C(N)C=1F.[ClH:29].Cl>[Zn].[Cl-].[NH4+].O.C(O)C>[ClH:29].[ClH:29].[NH2:1][C:4]1[CH:9]=[CH:8][C:7]([NH:10][CH2:11][CH2:12][CH:13]([OH:15])[CH3:14])=[CH:6][C:5]=1[CH3:16]

参加物

4

反応物 2

HCID 149026Tetrafluoro-m-phenylenediamine dihydrochlorideHCID 231043004-(4-Nitro-3-methylphenylamino)butan-2-ol

生成物 1

HCID 692204744-(4-Amino-3-methylphenylamino)butan-2-ol dihydrochloride

試薬・触媒・溶媒 1

HCID 131726756ZINC ammonium chloride water ethanol触媒

実験手順

The 4-(4-nitro-3-methylphenylamino)butan-2-ol (31) obtained above was reduced with a boiling zinc/ammonium chloride/water/ethanol mixture. The corresponding amine was isolated in dihydrochloride form.

出典と根拠

ORDレコード
ord-27288e91282f4737b90e6298ba645bfe
出典データセット
uspto-grants-2008_11
特許番号
US07445645B2

反応ノート

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