2-Methoxyfluorene → 1-(7-Methoxy-fluoren-2-yl)-ethanone

反応式

[CH:1]1[C:13]2[CH2:12][C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]=[CH:3][C:2]=1[O:14][CH3:15].[C:16](Cl)(=[O:18])[CH3:17].[Al+3].[Cl-].[Cl-].[Cl-]>>[CH3:15][O:14][C:2]1[CH:1]=[C:13]2[C:5]([C:6]3[CH:7]=[CH:8][C:9]([C:16](=[O:18])[CH3:17])=[CH:10][C:11]=3[CH2:12]2)=[CH:4][CH:3]=1

参加物

反応物 2

HCID 173012-Methoxyfluorene

HCID 86587523acetyl chloride AlCl3

生成物 1

HCID 215039141-(7-Methoxy-fluoren-2-yl)-ethanone

実験手順

1-(7-Methoxy-fluoren-2-yl)-ethanone is prepared by the acylation of fluoren-2-yl-methyl ether with acetyl chloride/AlCl3 according to Kajigaeshi, et al., Bull. Chem. Soc. Jpn., 52, 3569-3572 (1979) or Gray et al, J. Chem Soc., 1955; 2686-2688, both of which are incorporated herein by reference.

出典と根拠

ORDレコード: ord-01461745c2064a5aa115b8bd636e14d9
出典データセット: uspto-grants-2008_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07445825B2

反応ノート

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