2-Bromo-9H-fluorene → 2-Acetyl-7-bromofluorene

反応式

[Br:1][C:2]1[CH:14]=[CH:13][C:12]2[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[CH2:5][C:4]=2[CH:3]=1.[C:15](OC(=O)C)(=[O:17])[CH3:16].[Al+3].[Cl-].[Cl-].[Cl-].[N+](C1C=CC=CC=1)([O-])=O>>[Br:1][C:2]1[CH:3]=[C:4]2[C:12]([C:11]3[CH:10]=[CH:9][C:8]([C:15](=[O:17])[CH3:16])=[CH:7][C:6]=3[CH2:5]2)=[CH:13][CH:14]=1

参加物

反応物 2

HCID 143362-Bromo-9H-fluorene

HCID 86587524acetic anhydride AlCl3 nitrobenzene

生成物 1

HCID 2706752-Acetyl-7-bromofluorene

実験手順

1-(7-bromo-9H-fluoren-2-yl)-ethanone is prepared by the reaction of 2-bromofluorene (available from Aldrich Chemical Company, Milwaukee, Wis.) with acetic anhydride/AlCl3/nitrobenzene according to Tsuno et al., Bull. Chem. Soc. Jpn., 51, 601-607 (1978), incorporated herein by reference.

出典と根拠

ORDレコード: ord-3be9e6a1ff784fccb293c9e66a4165de
出典データセット: uspto-grants-2008_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07445825B2

反応ノート

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