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Benzoyl isothiocyanate → N-benzoyl-N'-[2-(2-thiazolylmethylthio)ethyl]thiourea
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzoyl isothiocyanate | HCID 68284 | — |
| 反応物 | 2-[(Thiazol-2-yl)methylthio]ethylamine | HCID 12923403 | — |
| 生成物 | N-benzoyl-N'-[2-(2-thiazolylmethylthio)ethyl]thiourea | HCID 20557654 | — |
反応手順
By the procedure of Example 18, 2-[(2-aminoethyl)thiomethyl]thiazole is reacted with benzoyl isothiocyanate to give N-benzoyl-N'-[2-(2-thiazolylmethylthio)ethyl]thiourea. Removing the benzoyl group by the procedure of Example 18 gives N-[2-(2-thiazolylmethylthio)ethyl]thiourea. Treating this compound with hydrobromic acid gives the hydrobromide salt.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04151288 |
| 出典データセット | uspto-grants-1979_04 |
| ORD ID | ord-f933faaac4e64b699e31d8e6aced79d2 |
| 出典メモ | uspto-grants-1979_04 |