3-Cyanophenylboronic acid → 2-[8-(3-Cyano-phenyl)-1-ethyl-6-isopropyl-1,3,4,9-tetrahydro-pyrano[3,4-B]indol-1-YL]-ethanol
反応式
Br[C:2]1[CH:3]=[C:4]([CH:20]([CH3:22])[CH3:21])[CH:5]=[C:6]2[C:10]=1[NH:9][C:8]1[C:11]([CH2:17][CH2:18][OH:19])([CH2:15][CH3:16])[O:12][CH2:13][CH2:14][C:7]2=1.[C:23]([C:25]1[CH:26]=[C:27](B(O)O)[CH:28]=[CH:29][CH:30]=1)#[N:24]>>[C:23]([C:25]1[CH:30]=[C:29]([C:2]2[CH:3]=[C:4]([CH:20]([CH3:21])[CH3:22])[CH:5]=[C:6]3[C:10]=2[NH:9][C:8]2[C:11]([CH2:17][CH2:18][OH:19])([CH2:15][CH3:16])[O:12][CH2:13][CH2:14][C:7]3=2)[CH:28]=[CH:27][CH:26]=1)#[N:24]参加物
3
実験手順
The title compound is prepared in a manner analogous to Example 1, except using 2-(8-bromo-1-ethyl-6-isopropyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indol-1-yl)-ethanol and 3-cyanophenylboronic acid in step 1.F.
出典と根拠
- ORDレコード
- ord-c6e5537cb8d9438abcd09f75c06a7cc2
- 出典データセット
- uspto-grants-2008_11