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Tryptophol → 8'-Ethyl-4',9'-dihydro-3'H-spiro(cyclohexane-1,1'-pyrano[3,4-b]indole)-4-carboxylic acid ethyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Tryptophol | HCID 10685 | — |
| 反応物 | 7-Ethyltryptophol | HCID 198231 | — |
| 反応物 | Ethyl 4-oxocyclohexanecarboxylate | HCID 317638 | — |
| 生成物 | 8'-Ethyl-4',9'-dihydro-3'H-spiro(cyclohexane-1,1'-pyrano[3,4-b]indole)-4-carboxylic acid ethyl ester | HCID 69196892 | — |
反応手順
Following the procedure of example 24.A. except using 2-(7-ethyl-1H-indol-3-yl)-ethanol as the 3-indolethanol component and 4-oxo-cyclohexane carboxylic acid ethyl ester as ketone component afforded the title compound as an oil. ESI (+) MS m/e=342 (MH+), ESI (−) MS m/e=340 (MH−).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07446122B2 |
| 出典データセット | uspto-grants-2008_11 |
| ORD ID | ord-5b0693fdf6b9439d8229470b8343cdf3 |
| 出典メモ | uspto-grants-2008_11 |